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Arimidex coated tablets
Anastrozole 1 mg,
28 pcs. packaged.
Arimidex has antitumor effect.
Adjuvant therapy for early hormone-positive breast cancer in postmenopausal women, treatment of advanced breast cancer in postmenopausal women.
Inside Swallow arimidex pill whole with water, at the same time. Adults (including the elderly) - 1 mg 1 time per day (for a long time). If there are signs of disease progression, Arimidex should be discontinued.
hypersensitivity to anastrozole or other parts of Arimidex,
in premenopausal women,
severe renal failure (Cl creatinine less than 20 ml / min),
moderate or severe liver failure (safety and efficacy not established),
concomitant therapy with Tamoxifen,
children's age (safety and efficacy in children has not been established).
On the part of the vascular system: very often - 'tides'.
From the musculoskeletal system: often - arthralgia.
Reproductive system: often - vaginal dryness, rarely, vaginal bleeding (mainly during the first weeks after the cancellation or change of previous hormonal therapy with Arimidex).
On the part of the skin and skin appendages: often - thinning hair, skin rash, very rarely - polymorphic erythema (Stevens-Johnson syndrome).
On the part of the digestive system: often - nausea, diarrhea, rarely - anorexia, vomiting, increased activity of gamma-glutamine transferase and alkaline phosphatase.
From the nervous system: often - headache, rarely - drowsiness.
Safety and efficacy in children has not been established.
In women with a receptor-negative tumor to estrogen, the efficacy of Arimidex has not been demonstrated, except in cases where there was a prior positive clinical response to tamoxifen.
The drug should be stored in a dry, dark place at a temperature not higher than 25 ° C.